SCP2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52211
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | DKFZp686C12188,DKFZp686D11188,NLTP,NLTP,Non-specific lipid-transfer protein,Nonspecific lipid transfer protein,NSL TP,NSL-TP,OTTHUMP00000010488,OTTHUMP00000231766,OTTHUMP00000231767,OTTHUMP00000231768,OTTHUMP00000231769,OTTHUMP00000231770,OTTHUMP00000231772,OTTHUMP00000231773,OTTHUMP00000231774,OTTHUMP00000231776,OTTHUMP00000234662,Propanoyl CoA C acyltransferase,Propanoyl-CoA C-acyltransferase,SCP 2,SCP chi ,SCP X,SCP-2,SCP-chi,SCP-X,SCP2,SCPchi ,SCPX,Sterol carrier protein 2,Sterol carrier protein X,SCP2抗体 |
| Swissprot | P22307 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human SCP2 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion; Cytoplasm. Mitochondrion. Cytoplasmic in the liver and also associated with mitochondria especially in steroidogenic tissues and Peroxisome. Interaction with PEX5 is essential for peroxisomal import. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. |
