SEMA4D Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52208
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | A8,BB 18,BB18,CD 100,CD100,CD100 antigen,Coll 4,COLL4,Collapsin 4,Collapsin4,GR3,Leukocyte activation antigen CD100,M sema G,MSEMA,SEM4D,Sema 4d,Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4D,Sema H,SEMA J,Sema4d,Semacl 2,Semacl2,SemaH,SEMAJ,Semaphorin 4D,Semaphorin C like 2,Semaphorin H,Semaphorin J,Semaphorin-4D,Semaphorin4D,SemaphorinJ,Semcl 2,Semcl2,SEMA4D抗体 |
| Swissprot | Q92854 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human SEMA4D |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:300 |
| Concentration | 0.4mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA. |
