SEPP1 Polyclonal Antibody
规格: | / 50μL / 100μL |
价格: | / ¥1010 / ¥1640 |
货号:D-AB-10379L
货期:咨询
宿主: Rabbit
反应性: H,R
应用: WB,IF
Overview
Synonyms | Selenoprotein P,SeP,SELENOP,SELP,SEPP1 |
Swissprot | P49908 |
Source | Rabbit |
Reactivity | Human,Rat |
Immunogen | Recombinant Human SEPP1 protein expressed by E.coli |
Application | WB(Detection kit: E-IR-R304),IF |
Recommended dilution | WB,,1:500-1:1000;IF,,1:50-1:200; |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Isotype | IgG |
Purification | Antigen Affinity Purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
Background | Selenoprotein P (SeP) is an extracellular,monomeric glycoprotein containing up to 10 selenocysteine residues in the polypeptide chain. It is ubiquitously expressed in mammalian tissues,and in human plasma it accounts for at least 40% of the total selenium concentration. SeP binds to heparin and cell membranes,and is associated with endothelial cells. SeP in human plasma protects against peroxynitrite-mediated oxidation and reduces phospholipid hydroperoxide in vitro,in accordance with the presumption that it has a function as an extracellular oxidant defense. Immunochemical assays have demonstrated that its concentration in plasma varies much with selenium intake,but other factors also have an influence. |