Serpin A1 Polyclonal Antibody
| 规格： | / 50μL / 100μL |
| 价格： | / ￥1010 / ￥1640 |
货号：E-AB-40634
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Alpha-1-antiproteinase,Alpha-1-proteinase inhibitor,Serpin A1 |
| Swissprot | P17475 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant Rat Serpin A1 protein expressed by E.coli |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:100-1:200;IHC,,1:2000-1:4000; |
| Concentration | 6.9mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted |
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | Serpin A1 is the archetypal member of the Serpin superfamily of the serine protease inhibitors. As one of the most abundant proteinase inhibitors in the circulation, it is synthesized in the liver and secreted into the bloodstream with the major function to protect tissues against neutrophil elastase.A severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatitis, cirrhosis, and hepatocellular carcinoma. |
Images
Western blot with anti-alpha 1 Antitrypsin Polyclonal antibody at dilution of 1:200.lane 1: Rat kidney tissue, lane 2:Mouse liver tissue, lane 3: Human plasma, lane 4:HepG2 whole cell lysate
Immunohistochemistry of paraffin-embedded Human liver tissue using Serpin A1 Polyclonal Antibody at dilution of 1:3500(×400)
