SERPINA3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10777
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | SERPINA3,AACT,AACT,ACT,Alpha-1-antichymotrypsin His-Pro-less,Antichymotrypsin,Cell growth inhibiting gene 24/25 protein,Cell growth-inhibiting gene 24/25 protein,GIG24,GIG25,Growth inhibiting protein 24,Growth inhibiting protein 25,MGC88254,Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase,antitrypsin) member 3,Serine (or cysteine) proteinase inhibitor clade A member 3,Serine proteinase inhibitor clade A member 3,Serpin A3,Serpin family A member 3,Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3,SERPINA3,SERPINA3抗体 |
| Swissprot | P01011 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human SERPINA3 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted. |
| Tissue specificity | Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. |
