SERPINB4 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52213
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | Leupin,Peptidase inhibitor 11,PI 11,PI-11,PI11,Protease inhibitor (leucine serpin),SCCA 2,SCCA-2,SCCA1,SCCA2,SCCA2/SCCA1 fusion protein,Serine (or cysteine) proteinase inhibitor,clade B (ovalbumin),member 4,Serpin B4,Serpin peptidase inhibitor,clade B (ovalbumin),member 4,SERPINB 4,SERPINB4,SPB4,Squamous cell carcinoma antigen 1,Squamous cell carcinoma antigen 2,SERPINB4抗体 |
| Swissprot | P48594 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Fusion protein of human SERPINB4 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:100 |
| Concentration | 0.72mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Seems to also be secreted in plasma by cancerous cells but at a low level. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation. SERPINB4 (Serpin Family B Member 4) is a Protein Coding gene. Diseases associated with SERPINB4 include Squamous Cell Carcinoma and Chromosome 18Q Deletion Syndrome. Among its related pathways are Amoebiasis. GO annotations related to this gene include enzyme binding and protease binding. An important paralog of this gene is SERPINB3. |
