SERPINB5 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10447
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | Maspin,Ovalbumin,Peptidase inhibitor 5,PI-5,PI5,protease inhibitor 5 (maspin),Protease inhibitor 5,Serine (or cysteine) peptidase inhibitor,clade B,member 5,serine (or cysteine) proteinase inhibitor,clade B (ovalbumin),member 5,Serpin B5,serpin family B member 5,Serpin peptidase inhibitor,Serpin peptidase inhibitor,clade B (ovalbumin),member 5,Serpinb5,SPB5,Spi5,Spi7,SERPINB5抗体 |
| Swissprot | P36952 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human SERPINB5 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:100-1:300; |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted>extracellular space. |
| Tissue specificity | Normal mammary epithelial cells. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Maspin (mammary serine protease inhibitor) also known as serpin B5 is a protein that in humans is encoded by the SERPINB5 gene.[1] This protein belongs to the serpin (serine protease inhibitor) superfamily.[1] SERPINB5 also functions as a tumor suppressor gene in epithelial cells. The expressed protein suppresses the ability of cancer cells to invade and metastasize other tissues. The protein also functions as an angiogenesis inhibitor.It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. |
Images
Western Blot analysis of Mouse esophagus and Human cervical cancer tissue using SERPINB5 Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human esophagus cancer using SERPINB5 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human lung cancer using SERPINB5 Polyclonal Antibody at dilution of 1:60
