SETD1A Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18095
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | Histone-lysine N-methyltransferase SETD1A,hSET1A,KMT2F ,Lysine N methyltransferase 2F,Lysine N-methyltransferase 2F,SET domain containing 1A,SET domain containing protein 1A,SET domain-containing protein 1A,SET1 ,Set1 Ash2 histone methyltransferase complex subunit SET1,Set1/Ash2 histone methyltransferase complex subunit SET1,SET1A ,SET1A,SETD1A,SETD1A抗体 |
| Swissprot | O15047 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human SETD1A |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 0.72mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus speckle. Chromosome. Localizes to a largely non-overlapping set of euchromatic nuclear speckles with SETD1B, suggesting that SETD1A and SETD1B each bind to a unique set of target genes. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily. |
