SETMAR Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18994
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | Histone lysine N methyltransferase,Histone lysine N methyltransferase SETMAR,Hsmar 1,Hsmar1,Mariner transposase Hsmar1,Metnase,SET domain and mariner transposase fusion,SET domain and mariner transposase fusion gene,SET domain and mariner transposase fusion gene containing protein,SET domain and mariner transposase fusion gene-containing protein,Setmar,SETMR,SETMAR抗体 |
| Swissprot | Q53H47 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human SETMAR |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:300 |
| Concentration | 1.08mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Chromosome. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. |
