SHPK Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-52517
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
Synonyms | Carbohydrate kinase like,Carbohydrate kinase like protein,Carbohydrate kinase-like protein,CARKL,Sedoheptulokinase,SHK,Shpk,SHPK,SHPK抗体 |
Swissprot | Q9UHJ6 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Fusion protein of human SHPK |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:40-1:200; |
Concentration | 1.1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. |