SIX6 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19997
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | Homeobox protein SIX6,Homeodomain protein OPTX2,MCOPCT 2,MCOPCT2,Optic homeobox 2,OPTX 2,OPTX2,Sine oculis homeobox homolog 6,SIX 6,Six 9,SIX homeobox 6,Six6,SIX6,Six9,SIX6抗体 |
Swissprot | O95475 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human SIX6 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:300 |
Concentration | 1.44mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2).SIX6 (SIX Homeobox 6) is a Protein Coding gene. Diseases associated with SIX6 include Optic Disc Anomalies With Retinal And/Or Macular Dystrophy and Six6-Related Eye Disorders. Among its related pathways are Ectoderm Differentiation. GO annotations related to this gene include transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding. An important paralog of this gene is SIX3. |