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SLC22A6 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-16016

宿主: Rabbit

反应性: H,R

应用: WB,IHC,ELISA

  • 详情
  • 文献(1)
  • Overview

    Synonyms FLJ55736,hOAT1,hPAHT,hROAT1,MGC45260,OAT1,Organic anion transporter 1,OTTHUMP00000236796,OTTHUMP00000236797,OTTHUMP00000236798,OTTHUMP00000236799,PAH transporter,PAHT,Para aminohippurate transporter,Renal organic anion transporter 1,ROAT1,S22A6,SLC22A6,Solute carrier family 22 (organic anion transporter) member 6,Solute carrier family 22 member 6,SLC22A6抗体
    Swissprot Q4U2R8
    Source Rabbit
    Reactivity Human,Rat
    Immunogen Synthetic peptide of human SLC22A6
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
    Recommended dilution WB 1:1000-1:5000, IHC 1:50-1:200
    Concentration 0.5 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane.
    Tissue specificity Strongly expressed in kidney and to a lower extent in liver, skeletal muscle, brain and placenta. Found at the basolateral membrane of the proximal tubule.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) By similarity.
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