SLC22A6 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-16016
宿主: Rabbit
反应性: H,R
应用: WB,IHC,ELISA
Overview
Synonyms | FLJ55736,hOAT1,hPAHT,hROAT1,MGC45260,OAT1,Organic anion transporter 1,OTTHUMP00000236796,OTTHUMP00000236797,OTTHUMP00000236798,OTTHUMP00000236799,PAH transporter,PAHT,Para aminohippurate transporter,Renal organic anion transporter 1,ROAT1,S22A6,SLC22A6,Solute carrier family 22 (organic anion transporter) member 6,Solute carrier family 22 member 6,SLC22A6抗体 |
Swissprot | Q4U2R8 |
Source | Rabbit |
Reactivity | Human,Rat |
Immunogen | Synthetic peptide of human SLC22A6 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA |
Recommended dilution | WB 1:1000-1:5000, IHC 1:50-1:200 |
Concentration | 0.5 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane. |
Tissue specificity | Strongly expressed in kidney and to a lower extent in liver, skeletal muscle, brain and placenta. Found at the basolateral membrane of the proximal tubule. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) By similarity. |
客户发表文献
- 文献: Molecular Nanoparticles of Ferric–Tannic Complexes Enhance Brain Magnetic Resonance Imaging and Activate Brain Clearance Pathways
样品类型: brain tissue,hCMEC/D3 cell