SMNDC1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18953
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | 30 kDa splicing factor SMNrp,MGC106917,MGC112663,SMN related protein,SMN-related protein,smndc1,SMNR,SPF30,SPF30,Splicing factor 30, survival of motor neuron-related ,Survival motor neuron domain containing 1,Survival motor neuron domain containing protein 1,Survival motor neuron domain-containing protein 1,Survival of motor neuron related splicing factor 30,Survival of motor neuron-related-splicing factor 30,SMNDC1抗体 |
Swissprot | O75940 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Fusion protein of human SMNDC1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:40-1:200 |
Concentration | 0.6mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus speckle. Nucleus>Cajal body. Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. |