SNAI1 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70119
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | dJ710H13.1,Protein sna,Protein snail homolog 1,Protein snail homolog,SLUGH2,SNA,Sna protein,SNAH,SNAI,snai1,SNAI1,Snail 1 homolog,Snail 1 zinc finger protein,SNAIL,Snail family transcriptional repressor 1,Snail homolog 1 (Drosophila),SNAIL,Drosophila,homolog of,1,SNAIL1,Zinc finger protein SNAI1,SNAI1抗体 |
| Swissprot | Q02085 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Snai1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:500-1:1000 |
| Concentration | 380 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasm. Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. |
| Tissue specificity | While expression is completely absent from non-invasive cell lines, it is high in invasive and metastatic cell types.Highest expression level in ectoplacental cone. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. |
