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SNX6 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-17861

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms Sorting Nexin 6,Tumor Necrosis Factor Receptor-Associated Factor 4(TRAF4)-Associated Factor 2,MSTP010,TFAF2,SNX6抗体
    Swissprot Q9UNH7
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Synthetic peptide of human SNX6
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:40-1:200
    Concentration 1.6mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm, Cytoplasmic vesicle, Endosome, Membrane, Nucleus
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms.
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