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SOX-7 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-10608

宿主: Rabbit

反应性: H,M

应用: WB

  • 详情
  • Overview

    Synonyms MGC10895,SOX 7,SOX 7 transcription factor,sox7,SOX7 transcription factor,SOX7,SRY (sex determining region Y) box 7,SRY box 7,SRY sex determining region Y box 7,Transcription factor SOX 7,Transcription factor Sox-7,Transcription factor SOX7,SOX7抗体
    Swissprot Q9BT81
    Source Rabbit
    Reactivity Human,Mouse
    Immunogen Recombinant protein of human SOX7
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:1000-1:5000;
    Concentration 0.5 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus.
    Tissue specificity Widely expressed in adult and fetal tissues. Present both in mesenchymal and epithelial cells in some adult tissues, including colon. Tends to be down-regulated in prostate adenocarcinomas and colorectal tumors due to promoter hypermethylation.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway.
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