SPCS2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18383
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Microsomal signal peptidase 25 kDa subunit,Signal peptidase complex subunit 2,Signal peptidase complex subunit 2 homolog (S. cerevisiae),SPase 25 kDa subunit,SPCS2,SPCS2,SPCS2抗体 |
| Swissprot | Q15005 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human SPCS2 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:30-1:150; |
| Concentration | 1.1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Microsome membrane. Endoplasmic reticulum membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | SPCS2 (signal peptidase complex subunit 2), also known as SPC25 or microsomal signal peptidase 25 kDa subunit, is a 226 amino acid multi-pass membrane protein that localizes to both the microsome and the endoplasmic reticulum (ER), and belongs to the SPCS (signal peptidase complex subunit) family. Existing as a component of the microsomal signal peptidase complex which consists of five members, SPCS2 removes signal peptides from nascent proteins as they are translocated into the lumen of the ER. The gene encoding SPCS2 is located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. |
Images
Western blot analysis of K-562 cell Human placenta tissue Mouse adrenal gland tissue HT-29 cell NIH/3T3 cell Rat lung tissue using SPCS2 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using SPCS2 Polyclonal Antibody at dilution of 1:40(×200)
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using SPCS2 Polyclonal Antibody at dilution of 1:40(×200)
