SPTAN1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-40268
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | (ALPHA)II-SPECTRIN,Alpha II Spectrin,Alpha-II spectrin,brain,EIEE5,FLJ17738,FLJ44613,Fodrin alpha chain,Fodrin,alpha,NEAS,Non erythrocytic spectrin alpha,non-erythroid alpha chain,SPECA,Spectrin alpha chain,Spectrin alpha chain brain,Spectrin alpha non erythrocytic 1,Spectrin,Spectrin non erythroid alpha chain,Spectrin,alpha,non-erythrocytic 1 (alpha-fodrin),Spectrin,nonerythroid,alpha subunit,Spna2,SPTA 2,SPTA2,SPTA2,SPTAN 1,SPTAN1,SPTAN1抗体 |
| Swissprot | P16086 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant Rat Spectrin alpha chain, non-erythrocytic 1 protein |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:2000;IHC,,1:100-1:400; |
| Concentration | 1mg/mL |
Properties
| Cellular localization | Cytoplasm>cytoskeleton. Cytoplasm>cell cortex. Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells. |
| Tissue specificity | Expressed in the foot process layer of podocytes in the kidney glomerulus and in tubules (at protein level).Highest expression level in brain. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. |
Images
Western Blot analysis of Mouse kidney using Sptan1 Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Rat kidney using Sptan1 Polyclonal Antibody at dilution of 1:100(100×)
Immunohistochemistry of paraffin-embedded Rat kidney using Sptan1 Polyclonal Antibody at dilution of 1:100(400×)
Immunohistochemistry of paraffin-embedded Human carcinoma of Colon using Sptan1 Polyclonal Antibody at dilution of 1:100（100×）
Immunohistochemistry of paraffin-embedded Human carcinoma of Colon using Sptan1 Polyclonal Antibody at dilution of 1:100（400×）
