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SREBF2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-53273

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms AI608257,bHLHd2,Class D basic helix-loop-helix protein 2,OTTHUMP00000028740,Processed sterol regulatory element-binding protein 2,SRBP2,SREBF 2,Srebf2,SREBF2 protein,SREBP 2,SREBP-2,SREBP2,SREBP2gc,sterol regulatory element binding factor 2,Sterol regulatory element binding protein 2,Sterol regulatory element binding transcription factor 2,Sterol regulatory element-binding transcription factor 2,SREBF2抗体
    Swissprot Q12772
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human SREBF2
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:300
    Concentration 1mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus and Endoplasmic reticulum membrane. Golgi apparatus membrane. Cytoplasmic vesicle>COPII-coated vesicle membrane. Moves from the endoplasmic reticulum to the Golgi in the absence of sterols.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants.
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