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ST18 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-15416

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms KIAA0535,St18,ST18,suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein),Suppression of tumorigenicity 18 protein,Suppression of tumorigenicity protein 18,Zinc finger protein 387,Znf387,ST18抗体
    Swissprot O60284
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant protein of human ST18
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:40-1:150
    Concentration 1.1 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus.
    Tissue specificity Detected at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate. Detected at even lower levels in mammary epithelial cells and breast cancer cells.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background ST18 (suppression of tumorigenicity 18), also known as ZNF387 ((zinc finger protein 387), is a 1,047 amino acid nuclear protein that is expressed at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate.Containing six C2HC-type zinc fingers and an SMC domain, ST18 is a repressor protein that binds to DNA sequences containing a specific bipartite element.ST18 is considered a transcription factor that represses basal transcription activity from target promoters and Inhibits colony formation in cultured breast cancer cells.
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