STAT6 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10059
宿主: Rabbit
反应性: H,M
应用: WB
Overview
| Synonyms | 12S1644,D12S1644,IL 4 STAT,IL-4 Stat,IL4 STAT,Interleukin 4 Induced,Interleukin 4 Induced Transcription Factor IL4 STAT,Signal transducer and activator of transcription 6,Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced,Signal Transducer And Activator Of Transcription 6 Nirs Variant 1,Signal transducer and activator of transcription 6,interleukin 4 induced,STAT 6,STAT interleukin4 induced,STAT,interleukin4 induced,Stat6,STAT6,STAT6B,STAT6C,Transcription factor IL 4 STAT,STAT6抗体 |
| Swissprot | P42226 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human STAT6 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants. |
