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STOM Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-40158

宿主: Rabbit

反应性: M,R

应用: WB,IHC

  • 详情
  • Overview

    Synonyms BND7,EPB7,EPB72,Erythrocyte band 7 integral membrane protein,Erythrocyte membrane protein band 7.2 (stomatin),Erythrocyte surface protein band 7.2,Protein 7.2b,STOM,STOM,Stomatin,STOM抗体
    Swissprot P27105
    Source Rabbit
    Reactivity Mouse,Rat
    Immunogen Recombinant human Erythrocyte band 7 integral membrane protein
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB 1:500-1:1000, IHC 1:50-1:100
    Concentration 2 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell membrane. Cell membrane. Melanosome. Exposed on the cytoplasmic surface of the membrane. Associated with lipid rafts. Concentrates preferentially in plasma membrane protrusions and in a juxta-nuclear region which may represent Golgi-derived vesicles. Colocalizes with actin. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    Tissue specificity Widely expressed.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    Background This gene encodes a member of a highly conserved family of integral membrane proteins. The encoded protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of the encoded protein is associated with hereditary stomatocytosis, a form of hemolytic anemia. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants.
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