STOM Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-40158
宿主: Rabbit
反应性: M,R
应用: WB,IHC
Overview
Synonyms | BND7,EPB7,EPB72,Erythrocyte band 7 integral membrane protein,Erythrocyte membrane protein band 7.2 (stomatin),Erythrocyte surface protein band 7.2,Protein 7.2b,STOM,STOM,Stomatin,STOM抗体 |
Swissprot | P27105 |
Source | Rabbit |
Reactivity | Mouse,Rat |
Immunogen | Recombinant human Erythrocyte band 7 integral membrane protein |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB 1:500-1:1000, IHC 1:50-1:100 |
Concentration | 2 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane. Cell membrane. Melanosome. Exposed on the cytoplasmic surface of the membrane. Associated with lipid rafts. Concentrates preferentially in plasma membrane protrusions and in a juxta-nuclear region which may represent Golgi-derived vesicles. Colocalizes with actin. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Tissue specificity | Widely expressed. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background | This gene encodes a member of a highly conserved family of integral membrane proteins. The encoded protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of the encoded protein is associated with hereditary stomatocytosis, a form of hemolytic anemia. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants. |
Images
Western Blot analysis of Rat heart using STOM Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Mouse brain using STOM Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Rat lung using STOM Polyclonal Antibody at dilution of 1:50