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Succinylated Lysine Polyclonal Antibody

规格: / 20μL / 50μL / 100μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-40542

宿主: Rabbit

反应性: H

应用: WB

  • 详情
  • Overview

    Synonyms anti-succinyllysine antibody
    Source Rabbit
    Reactivity Human
    Immunogen Succinylated BSA
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:1000-2000;
    Concentration 2mg/mL
    Clonality Polyclonal

    Properties

    Isotype IgG
    Purification Antigen Affinity Purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
    Background Succinylation is a posttranslational modification where a succinyl group (-CO-CH2-CH2-CO2H) is added to a lysine residue of a protein molecule. This modification is found in many proteins, including histones. Protein succinylation is especially prevalent among mitochondrial metabolic proteins and bacteria, further solidifying the evolutionary link between mitochondria and prokaryotes. It often occurs at lysine residues that are alternatively acetylated or ubiquitinated. More than a thousand lysine succinylation sites were identified on hundreds of proteins including glutamate dehydrogenase (15 sites), malate dehydrogenase, citrate synthase, carbamoyl phosphate synthase 1, and histone proteins.
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