SUMO2/3/4 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-12439
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | SMT3A,Smt3B,SMT3H1,SUMO-3,HSMT3,SMT3B,SUMO3,Smt3A,SMT3H2,IDDM5,SMT3H4,SUMO-4,dJ281H8.4,SUMO2/3/4抗体 |
Swissprot | P61956,P55854,Q6EEV6 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human SUMO2/SUMO3/SUMO4 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300; |
Concentration | 0.4 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Extracellular region or secreted,extracellular exosome,Nucleus,nucleoplasm,nucleus,PML body,Other locations:cytoplasm,kinetochore |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Images
Western Blot analysis of Human ovarian cancer tissue and SKOV3 cell using SUMO2/3/4 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human colon cancer using SUMO2/3/4 Polyclonal Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded Human thyroid cancer using SUMO2/3/4 Polyclonal Antibody at dilution of 1:100