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SUMO2/3/4 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-12439

宿主: Rabbit

反应性: H,M,R

应用: WB,IHC

  • 详情
  • Overview

    Synonyms SMT3A,Smt3B,SMT3H1,SUMO-3,HSMT3,SMT3B,SUMO3,Smt3A,SMT3H2,IDDM5,SMT3H4,SUMO-4,dJ281H8.4,SUMO2/3/4抗体
    Swissprot P61956,P55854,Q6EEV6
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human SUMO2/SUMO3/SUMO4
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:100-1:300;
    Concentration 0.4 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Extracellular region or secreted,extracellular exosome,Nucleus,nucleoplasm,nucleus,PML body,Other locations:cytoplasm,kinetochore
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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