SYNPO2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16895
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | DKFZp686G051,Genethonin 2,Genethonin-2,Myopodin,striated muscle specific,Synaptopodin-2,SYNP2,SYNPO 2,Synpo2,SYNPO2抗体 |
| Swissprot | Q9UMS6 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human SYNPO2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:25-1:100 |
| Concentration | 1.4mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm in a differentiation-dependent and stress-induced fashion. Localizes to the Z-disk in mature striated muscle. The nuclear export is XPO1-dependent (By similarity). Localized in a fiber-like pattern. partly overlapping with filamentous actin. |
| Tissue specificity | Skeletal muscle-specific. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Synaptopodin-2 is a protein that in humans is encoded by the SYNPO2 gene.Has an actin-binding and actin-bundling activity.Synaptopodin is a proline-rich, actin-associated protein expressed in mature dendritic spines and renal podocytes.Synaptopodin appears to play a role in the actin-based plasticity of spines by linking actin to the spine apparatus. |
