TBCC Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-53160
宿主: Rabbit
反应性: H
应用: IHC
Overview
Synonyms | Beta tubulin cofactor C,CFC,TBCC,TBCC,Tubulin folding cofactor C,Tubulin specific chaperone c,Tubulin-folding cofactor C,Tubulin-specific chaperone C,TBCC抗体 |
Swissprot | Q15814 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Fusion protein of human TBCC |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:100-1:200 |
Concentration | 1.2mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. Detected predominantly in the photoreceptor connecting cilium. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. |