TBP Monoclonal Antibody
| 规格： | / 20μL / 60μL / 120μL |
| 价格： | / ￥580 / ￥1420 / ￥2310 |
货号：E-AB-22171
宿主: Mouse
反应性: H,M,R
应用: IHC-p
Overview
| Synonyms | GTF2D,GTF2D1,HDL4,SCA17,TATA binding factor,TATA box binding protein,TATA box factor,TATA sequence binding protein,TATA sequence-binding protein,TATA-binding factor,TATA-box factor,TATA-box-binding protein,TBP,TBP,TFIID,Transcription initiation factor TFIID TBP subunit,TBP/TATA Binding Protein抗体 |
| Swissprot | P20226 |
| Source | Mouse |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant Protein |
| Application | IHC-p(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-200 |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Cellular localization | Nucleus. |
| Tissue specificity | Widely expressed, with levels highest in the testis and ovary. |
| Isotype | IgG |
| Purification | Protein A purification |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Background | This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. |
