TCAP Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18784
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | 19 kDa sarcomeric protein ,CMD1N,CMH25,LGMD2G,Limb girdle muscular dystrophy 2G (autosomal recessive) ,T-cap,Tcap,TELE,Telethonin,TELT,Titin cap protein,Titin-cap,TCAP抗体 |
| Swissprot | O15273 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human TCAP |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 1.02mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm>myofibril>sarcomere. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. |
