TCEB2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18260
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | EloB,ELOB,Elongin 18 kDa subunit,Elongin B,Elongin-B,RNA polymerase II transcription factor SIII p18 subunit,RNA polymerase II transcription factor SIII subunit B,SIII,SIII p18,TCEB 2,Tceb2,Transcription elongation factor B (SIII) polypeptide 2,Transcription elongation factor B polypeptide 2,TCEB2抗体 |
| Swissprot | Q15370 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Full length fusion protein |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 0.9mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. |
