TCF7 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53275
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | FLJ36364,MGC47735,OTTHUMP00000159391,T cell factor 1,T cell specific transcription factor 1,T-cell factor 1,T-cell-specific transcription factor 1,TCF-1,TCF-7,TCF1,Tcf7,TCF7 transcription factor 7,TCF7,Transcription factor 7 (T cell specific HMG box),Transcription factor 7,Transcription factor-7,T-cell specific,Transcription factor-7,T-cell specific,1,TCF7抗体 |
| Swissprot | P36402 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human TCF7 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:40-1:200 |
| Concentration | 0.78mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators.This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development.The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway.Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation.Alternative splicing results in multiple transcript variants.Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling. |
