TCOF1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18871
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | Mandibulofacial dysostosis,MFD1,Nucleolar trafficking phosphoprotein,TCOF 1,TCOF,TCOF1,TCS,TCS1,Treacher Collins Franceschetti syndrome 1,Treacher Collins syndrome,Treacher Collins syndrome protein,Treacle,Treacle protein,TCOF1抗体 |
| Swissprot | Q13428 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Fusion protein of human TCOF1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:300 |
| Concentration | 0.9mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus>nucleolus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene. |
