TERF2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15871
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | Telomeric DNA binding protein,Telomeric DNA-binding protein,Telomeric repeat binding factor 2,Telomeric repeat binding protein 2,Telomeric repeat-binding factor 2,TERF 2,Terf2,TERF2,TRBF 2,TRBF2,TRF 2,TRF2,TTAGGG repeat binding factor 2,TTAGGG repeat-binding factor 2,TERF2抗体 |
| Swissprot | Q15554 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human TERF2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Chromosome>telomere. Colocalizes with telomeric DNA in interphase cells and is located at chromosome ends during metaphase. |
| Tissue specificity | Ubiquitous. Highly expressed in spleen, thymus, prostate, uterus, testis, small intestine, colon and peripheral blood leukocytes. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. |
