TGFBI Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18249
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | >RGD containing collagen associated protein,AI181842,AI747162,Beta ig,Beta ig h3,Beta ig-h3,BGH3,Big h3,BIGH3,CDB1,CDG2,CDGG1,CSD,CSD1,CSD2,CSD3,EBMD,Kerato epithelin,Kerato-epithelin,LCD1,MGC150270,RGD CAP,RGD-CAP,RGD-containing collagen-associated protein,TGFBI,TGFBI transforming growth factor,beta induced,68kDa,Transforming growth factor beta induced protein ig h3,Transforming growth factor-beta-induced protein ig-h3,TGFBI抗体 |
| Swissprot | Q15582 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human TGFBI |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
| Concentration | 1.02mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted>extracellular space>extracellular matrix. May be associated both with microfibrils and with the cell surface. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | TGFBI,also named as BIGH3,Kerato-epithelin and RGD-CAP,binds to type I,II,and IV collagens. TGFBI is an adhesion protein which may play an important role in cell-collagen interactions. In cartilage,it may be involved in endochondral bone formation. TGFBI is an extracellular matrix adaptor protein,it has been reported to be differentially expressed in transformed tissues. TGFBI is a predictive factor of the response to chemotherapy,and suggest the use of TGFBI-derived peptides as possible therapeutic adjuvants for the enhancement of responses to chemotherapy. Defects in TGFBI are the cause of epithelial basement membrane corneal dystrophy (EBMD). Defects in TGFBI are the cause of corneal dystrophy Groenouw type 1 (CDGG1). Defects in TGFBI are the cause of corneal dystrophy lattice type 1 (CDL1). Defects in TGFBI are a cause of corneal dystrophy Thiel-Behnke type (CDTB). Defects in TGFBI are the cause of Reis-Buecklers corneal dystrophy (CDRB). Defects in TGFBI are the cause of lattice corneal dystrophy type 3A (CDL3A). Defects in TGFBI are the cause of Avellino corneal dystrophy (ACD). |
