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THG1L Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19210

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms ICF45,Interphase cytoplasmic foci protein 45,Probable tRNA(His) guanylyltransferase,THG1,THG1L,tRNA histidine guanylyltransferase 1 like (S. cerevisiae),tRNA-histidine guanylyltransferase,THG1L抗体
    Swissprot Q9NWX6
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Fusion protein of human THG1L
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:200
    Concentration 1.26mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm. Found near the nuclear membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another function of this protein is that of a guanyltransferase, adding GMP to the 5' end of tRNA(His). Several transcript variants encoding different isoforms have been found for this gene.
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