TIMP-1 Polyclonal Antibody(Capture/Detector)
规格: | / 25μg / 100μg |
价格: | / ¥800 / ¥2100 |
货号:AN000670P
货期:咨询
宿主: Rabbit
反应性: H
应用: ELISA Capture/Detector
Overview
Synonyms | TIMP1;CLGI;EPA;EPO;HCI; |
Swissprot | P01033 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Recombinant Human TIMP-1 protein expressed by Mammalian |
Application | ELISA Capture/Detector |
Recommended dilution | ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Isotype | IgG |
Purification | Antigen Affinity Purification |
Conjugation | Unconjugated |
Storage instructions | Store at 4°C Valid for 1 month or -20°C Valid for 12 months,Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
Storage buffer | Sterile PBS,pH 7.4 |
Background | This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. |