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TIMP-1 Polyclonal Antibody(Capture/Detector)

规格: / 25μg / 100μg
价格: / ¥800 / ¥2100

货号:AN000670P

货期:咨询

宿主: Rabbit

反应性: H

应用: ELISA Capture/Detector

  • 详情
  • Overview

    Synonyms TIMP1;CLGI;EPA;EPO;HCI;
    Swissprot P01033
    Source Rabbit
    Reactivity Human
    Immunogen Recombinant Human TIMP-1 protein expressed by Mammalian
    Application ELISA Capture/Detector
    Recommended dilution ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL
    Concentration 1mg/mL
    Clonality Polyclonal

    Properties

    Isotype IgG
    Purification Antigen Affinity Purification
    Conjugation Unconjugated
    Storage instructions Store at 4°C Valid for 1 month or -20°C Valid for 12 months,Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
    Storage buffer Sterile PBS,pH 7.4
    Background This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
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