TLR2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-13835
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | CD282,CD282 antigen,TIL 4,TIL4,TLR 2,TLR2,TLR2,Toll like receptor 2,Toll like receptor 2 precursor,Toll-like receptor 2,Toll/interleukin 1 receptor like 4,Toll/interleukin 1 receptor like protein 4,Toll/interleukin receptor like protein 4,Toll/interleukin-1 receptor-like protein 4,TLR2抗体 |
| Swissprot | O60603 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human TLR2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:25-1:100 |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | Highly expressed in peripheral blood leukocytes, in particular in monocytes, in bone marrow, lymph node and in spleen. Also detected in lung and in fetal liver. Levels are low in other tissues. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity.TLRs are highly conserved from Drosophila to humans and share structural and functional similarities.They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.The various TLRs exhibit different patterns of expression.This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. |
