TMED10 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19178
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | 1110014C03Rik ,21 kDa transmembrane trafficking protein,21 kDa transmembrane-trafficking protein,MGC102351,p23,p24 family protein delta 1,p24 family protein delta-1,p24(DELTA),p24delta,p24delta1,S31I125,S31III125,TMED 10,Tmed10,TMEDA,Tmp 21 I,Tmp 21,Tmp 21 I,Tmp-21-I,Transmembrane emp24 domain containing protein 10,Transmembrane emp24 domain-containing protein 10,Transmembrane emp24-like trafficking protein 10 (yeast),Transmembrane protein Tmp21,Transmembrane trafficking protein 21kD,TMED10抗体 |
| Swissprot | P49755 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human TMED10 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:200; |
| Concentration | 1.14mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Golgi apparatus>cis-Golgi network membrane. Melanosome. Endoplasmic reticulum membrane. Endoplasmic reticulum-Golgi intermediate compartment membrane. Cytoplasmic vesicle>secretory vesicle membrane. Cell membrane. Golgi apparatus>trans-Golgi network membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Cycles between compartments of the early secretatory pathway. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. |
Images
Western blot analysis of NIH/3T3 cell Mouse Pancreas tissue Rat lung tissue Mouse liver tissue Hela Raji cell lysates using TMED10 Polyclonal Antibody at dilution of 1:900
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TMED10 Polyclonal Antibody at dilution of 1:65(×200)
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TMED10 Polyclonal Antibody at dilution of 1:65(×200)
