TMPRSS4 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-17112
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | UNQ776/PRO1570,CAPH2,Channel-activating protease 2,Membrane type serine protease 2,Membrane-type serine protease 2,MT SP2,MT-SP2,TMPRSS 4,TMPRSS3,TMPRSS4,TMPS4,Transmembrane protease serine 4,Transmembrane protease,serine 4,Transmembrane serine protease 3,TMPRSS4抗体 |
Swissprot | Q9NRS4 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | Fusion protein of human TMPRSS4 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:30-150 |
Concentration | 0.5mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Membrane. |
Tissue specificity | High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene. |