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TMX3 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19158

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms KIAA1830,PDIA13,Protein disulfide isomerase family A, member 13,Protein disulfide-isomerase TMX3,Thioredoxin domain containing 10,Thioredoxin domain-containing protein 10,Thioredoxin-related transmembrane protein 3,TMX3,TMX3,TXNDC10,TMX3抗体
    Swissprot Q96JJ7
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Fusion protein of human TMX3
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:200
    Concentration 1.26mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Endoplasmic reticulum membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The canonical protein encoded by this gene has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This gene is expressed in many tissues but has its highest expression in heart and skeletal muscle. It is expressed in the retinal neuroepithelium and lens epithelium in the developing murine eye and haploinsufficiency of this gene in humans and zebrafish is associated with microphthalmia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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