TMX3 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19158
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | KIAA1830,PDIA13,Protein disulfide isomerase family A, member 13,Protein disulfide-isomerase TMX3,Thioredoxin domain containing 10,Thioredoxin domain-containing protein 10,Thioredoxin-related transmembrane protein 3,TMX3,TMX3,TXNDC10,TMX3抗体 |
Swissprot | Q96JJ7 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Fusion protein of human TMX3 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 1.26mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Endoplasmic reticulum membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The canonical protein encoded by this gene has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This gene is expressed in many tissues but has its highest expression in heart and skeletal muscle. It is expressed in the retinal neuroepithelium and lens epithelium in the developing murine eye and haploinsufficiency of this gene in humans and zebrafish is associated with microphthalmia. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |