TNNC1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18400
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
Synonyms | tnnc1a,Cardiac troponin C,slow skeletal and cardiac muscles,TN-C,TNC,Tnnc1,TNNC1,TNNI3,Troponin C,Troponin C slow,Troponin C1 slow,TNNC1抗体 |
Swissprot | P63316 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Full length fusion protein |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:10-1:50; |
Concentration | 0.8mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoskeleton,cardiac Troponin complex,troponin complex,Cytosol |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. |