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TPO Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-14412

宿主: Rabbit

反应性: H

应用: IHC,ELISA

  • 详情
  • Overview

    Synonyms MSA,PERT,TDH2A,Thyroid microsomal antigen,Thyroid peroxidase,Thyroperoxidase,TPO,TPX,TPO抗体
    Swissprot P07202
    Source Rabbit
    Reactivity Human
    Immunogen Recombinant protein of human TPO
    Application IHC(Detection kit: E-IR-R213),ELISA
    Recommended dilution IHC 1:25-1:100
    Concentration 0.2 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Membrane and Cell surface.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.
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