TPX2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-17129
宿主: Rabbit
反应性: H,M
应用: WB
Overview
| Synonyms | C20ORF1,C20orf2,Chromosome 20 Open Reading Frame 1,Differentially expressed in cancerous and non-cancerous lung cells 2,Differentially expressed in cancerous and noncancerous lung cells 2,Differentially expressed in lung cells 2,Differentially expressed in lung cells,DIL 2,DIL-2,DIL2,FLS353,GD:C20orf1,HCA 519,HCA519,HCTP 4,HCTP4,Hepatocellular carcinoma associated antigen 519,Hepatocellular carcinoma-associated antigen 519,p100,Preferentially expressed in colorectal cancer,Protein fls353,REPP 86,repp86,Restricted expression proliferation associated protein 100,Restricted expression proliferation-associated protein 100,Targeting protein for Xklp2,TPX 2,TPX2,TPX2 microtubule associated homolog,TPX2 microtubule associated protein homolog,TPX2 microtubule nucleation factor,TPX2,TPX2抗体 |
| Swissprot | Q9ULW0 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Fusion protein of human TPX2 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-2000; |
| Concentration | 0.9 mg/mL |
| Clonality | Polyclonal |
Properties
| Tissue specificity | Expressed in lung carcinoma cell lines but not in normal lung tissues. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Background | TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules.Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase.Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly.TPX2 appears to play a structural role in spindle formation.TPX2 activates Eg2 in a microtubule-dependent manner by stimulating the phosphorylation and kinase activity of Eg2. |
