TRIM23 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18298
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | ADP ribosylation factor domain protein 1,ADP-ribosylation factor domain-containing protein 1,ARF domain protein 1,ARFD1,E3 ubiquitin-protein ligase TRIM23,GTP binding protein ARD 1,GTP-binding protein ARD-1,N-acetyltransferase ARD1 human homolog of,N-acetyltransferase homolog of S. cerevisiae ARD1,RING finger protein 46,TRI23,TRIM23,Tripartite motif protein TRIM23,Tripartite motif-containing protein 23,TRIM23抗体 |
| Swissprot | P36406 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human TRIM23 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:35-1:200 |
| Concentration | 0.8mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Endomembrane system. Golgi apparatus membrane. Lysosome membrane. Membrane-associated with the Golgi complex and lysosomal structures. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. |
