TRIM27 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18297
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | AW538890,DAAP-182E11.3,MGC189472,OTTHUMP00000029314,Ret finger protein,RFP,RFP transforming protein,Rfp1,RING finger protein 76,RNF76,TRI27,TRIM 27,Trim27,Tripartite motif containing 27,Tripartite motif containing protein 27,Tripartite motif protein TRIM27,Tripartite motif-containing protein 27,Zinc finger protein RFP,TRIM27抗体 |
| Swissprot | P14373 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human TRIM27 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:45-1:300; |
| Concentration | 1.1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasm. Nucleus>PML body. Nuclear or cytoplasmic depending on the cell type (By similarity). Colocalized with PML and EIF3S6 in nuclear bodies. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein. |
Images
Western blot analysis of 293T and A172 cell lysates using TRIM27 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TRIM27 Polyclonal Antibody at dilution of 1:65(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TRIM27 Polyclonal Antibody at dilution of 1:65(×200)
