TRIM63 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15990
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | E3 ubiquitin-protein ligase TRIM63,FLJ32380,IRF,Iris RING finger protein,MURF 1,MURF-1,MuRF1,MURF2,Muscle specific ring finger protein 1,Muscle specific ring finger protein 2,Muscle-specific RING finger protein 1,OTTHUMP00000008701,RING finger protein 28,RNF 28,RNF28,SMRZ,Striated muscle RING zinc finger protein,TRI63,TRIM 63,Trim63,Tripartite motif containing 63,tripartite motif containing 63,E3 ubiquitin protein ligase,Tripartite motif containing protein 63,Tripartite motif-containing protein 63,Ubiquitin ligase TRIM63,TRIM63抗体 |
| Swissprot | Q969Q1 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human TRIM63 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:25-1:100; |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. Localizes to the M- and Z-lines in skeletal muscle. Colocalizes with TNNI3 in myocytes. |
| Tissue specificity | Muscle specific. Selectively expressed in heart and skeletal muscle. Also expressed in the iris. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. |
