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TRIP6 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-17156

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms MGC10556,MGC10558,MGC29959,MGC3837,MGC4423,OIP-1,OIP1,OPA interacting protein 1,OPA-interacting protein 1,Thyroid hormone receptor interactor 6,Thyroid receptor interacting protein 6,Thyroid receptor-interacting protein 6,TR-interacting protein 6,TRIP-6,Trip6,TRIP6,TRIP6i2,ZRP 1,ZRP-1,Zyxin-related protein 1,TRIP6抗体
    Swissprot Q15654
    Source Rabbit
    Reactivity Human,Mouse
    Immunogen Fusion protein of human TRIP6
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:30-150
    Concentration 0.8mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm>cytoskeleton. Cell junction>focal adhesion. Nucleus. Cytoplasm. Shuttles between nucleus and cytoplasm.
    Tissue specificity Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas. Expressed in colonic epithelial cells. Up-regulated in colonic tumors.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
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