TRPC6 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16106
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | bZ1P14.9,FLJ11098,FLJ14863,FSGS2,MTRP6,Short transient receptor potential channel 6,si:rp71-1p14.9,Transient receptor potential cation channel subfamily C member 6,Transient receptor protein 6,TRP 6,TRP-6,TRP6,TRPC 6,Trpc6,TRPC6,TRRP6,TRPC6抗体 |
| Swissprot | Q9Y210 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human TRPC6 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | Expressed primarily in placenta, lung, spleen, ovary and small intestine. Expressed in podocytes and is a component of the glomerular slit diaphragm. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). |
