TRPM5 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12915
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | 9430099A16Rik,Long transient receptor potential channel 5,LTrpC-5,LTrpC5,MLSN1 and TRP related gene 1,MLSN1 and TRP related gene 1 protein,MLSN1 and TRP-related,MLSN1- and TRP-related gene 1 protein,MTR1,Novel protein similar to vertebrate transient receptor potential cation channel,subfamily M,member 5,Transient receptor potential cation channel subfamily M member 5,Transient receptor potential cation channel,subfamily M,member 5,Trpm5,TRPM5 transient receptor potential cation channel,subfamily M,member 5,TRPM5,TRPM5抗体 |
| Swissprot | Q9NZQ8 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Synthetic peptide of human TRPM5 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. |
| Tissue specificity | Strongly expressed in fetal brain, liver and kidney, and in adult prostate, testis, ovary, colon and peripheral blood leukocytes. Also expressed in a large proportion of Wilms' tumors and rhabdomyosarcomas. In monochromosomal cell lines shows exclusive paternal expression. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele. |
Images
Western Blot analysis of Mouse heart tissue using TRPM5 Polyclonal Antibody at dilution of 1:1200
Immunohistochemistry of paraffin-embedded Human thyroid cancer using TRPM5 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human gastric cancer using TRPM5 Polyclonal Antibody at dilution of 1:60
