TSC22D3 Polyclonal Antibody
规格: | / 60μL / 120μL / 200μL |
价格: | / ¥1380 / ¥2220 / ¥3300 |
货号:E-AB-70164
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
Synonyms | Delta sleep-inducing peptide immunoreactor,DIP,DSIP immunoreactive leucine zipper protein,DSIP-immunoreactive peptide,Dsip1,Dsipi,GILZ,Glucocorticoid-induced leucine zipper protein,hDIP,Protein DIP,T22D3,TSC-22-like protein,TSC-22-related protein,TSC-22R,TSC22 domain family protein 3,TSC22 domain family,member 3,TSC22 related inducible leucine zipper 3,TSC22D3,TSC22D3抗体 |
Swissprot | Q9Z2S7,Q9EQZ1 |
Source | Rabbit |
Reactivity | Mouse,Rat |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse GILZ |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:300-1:800 |
Concentration | 410 μg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytosol,Nucleus,Other locations:cytoplasm |
Tissue specificity | Constitutively expressed in lung, intestine, kidney and liver, most probably by resident cells from the macrophage lineage. Expression inversely correlates with T-cell activation, being higher in resting cells and lower in cells activated by TCR/CD3 triggering. Isoform 1 and isoform 4 are expressed in spleen and skeletal muscle (at protein level). Isoform 1 is expressed in thymus, lymph nodes, bone marrow, spleen, lung and skeletal muscle.Highest expression level in skin of back. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Background | The protein encoded by this gene shares significant sequence identity with the murine TSC-22 and Drosophila shs, both of which are leucine zipper proteins, that function as transcriptional regulators.The expression of this gene is stimulated by glucocorticoids and interleukin 10, and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid and chemokine.Transcript variants encoding different isoforms have been identified for this gene. |
Images
Immunohistochemistry analysis of paraffin-embedded mouse lung using TSC22D3 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded mouse spleen using TSC22D3 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat brain using TSC22D3 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat testis using TSC22D3 Polyclonal Antibody at dilution of 1:300.