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TSC22D3 Polyclonal Antibody

规格: / 60μL / 120μL / 200μL
价格: / ¥1380 / ¥2220 / ¥3300

货号:E-AB-70164

宿主: Rabbit

反应性: M,R

应用: IHC

  • 详情
  • Overview

    Synonyms Delta sleep-inducing peptide immunoreactor,DIP,DSIP immunoreactive leucine zipper protein,DSIP-immunoreactive peptide,Dsip1,Dsipi,GILZ,Glucocorticoid-induced leucine zipper protein,hDIP,Protein DIP,T22D3,TSC-22-like protein,TSC-22-related protein,TSC-22R,TSC22 domain family protein 3,TSC22 domain family,member 3,TSC22 related inducible leucine zipper 3,TSC22D3,TSC22D3抗体
    Swissprot Q9Z2S7,Q9EQZ1
    Source Rabbit
    Reactivity Mouse,Rat
    Immunogen KLH conjugated Synthetic peptide corresponding to Mouse GILZ
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:300-1:800
    Concentration 410 μg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytosol,Nucleus,Other locations:cytoplasm
    Tissue specificity Constitutively expressed in lung, intestine, kidney and liver, most probably by resident cells from the macrophage lineage. Expression inversely correlates with T-cell activation, being higher in resting cells and lower in cells activated by TCR/CD3 triggering. Isoform 1 and isoform 4 are expressed in spleen and skeletal muscle (at protein level). Isoform 1 is expressed in thymus, lymph nodes, bone marrow, spleen, lung and skeletal muscle.Highest expression level in skin of back.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
    Background The protein encoded by this gene shares significant sequence identity with the murine TSC-22 and Drosophila shs, both of which are leucine zipper proteins, that function as transcriptional regulators.The expression of this gene is stimulated by glucocorticoids and interleukin 10, and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid and chemokine.Transcript variants encoding different isoforms have been identified for this gene.
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