TTC12 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-52773
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
Synonyms | tetratricopeptide repeat domain 12,Tetratricopeptide repeat protein 12,tetratricopeptide repeat protein 12 variant 1,tetratricopeptide repeat protein 12 variant 2,TPARM,TPR repeat protein 12,TTC12,TTC12,TTC12抗体 |
Swissprot | Q9H892 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Fusion protein of human TTC12 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:30-1:150; |
Concentration | 0.72mg/mL |
Clonality | Polyclonal |
Properties
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | TTC12 (tetratricopeptide repeat domain 12), also known as TPARM, is a 705 amino acid cytoplasmic protein containing a TPR repeat domain and three armadillo repeat motifs. TTC12 is expressed in testis, prostate, lung, germinal center B cells, neuroblastoma, teratocarcinoma, colon cancer and gastric cancer. The gene encoding TTC12 is located in a region of human chromosome 11 that is commonly deleted in a variety of cancers, therefore, it is considered a candidate tumor suppressor gene. Human chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. |